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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALMS1
All Species:
1.82
Human Site:
S3658
Identified Species:
6.67
UniProt:
Q8TCU4
Number Species:
6
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCU4
NP_055935.4
4167
460937
S3658
D
D
S
R
G
E
R
S
V
K
E
W
S
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105121
4171
460833
D3662
D
D
S
R
G
E
R
D
V
K
E
W
S
G
R
Dog
Lupus familis
XP_533005
4146
460255
D3640
D
D
S
R
G
E
R
D
V
K
E
W
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4E0
3251
360220
S2801
S
P
H
Q
G
G
K
S
S
Q
F
K
I
E
Q
Rat
Rattus norvegicus
NP_001100074
2564
281531
Q2114
V
D
G
H
V
R
K
Q
H
Y
P
L
S
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420887
2322
257210
E1872
C
H
T
N
E
I
S
E
H
R
Q
Y
L
D
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690375
1912
209603
P1462
R
L
I
H
N
T
T
P
T
D
H
S
V
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.1
67
N.A.
48.3
37.3
N.A.
N.A.
21.5
N.A.
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
95.7
76.7
N.A.
58.4
45.5
N.A.
N.A.
34.5
N.A.
31.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
13.3
13.3
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
40
20
N.A.
N.A.
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
58
0
0
0
0
0
29
0
15
0
0
0
15
0
% D
% Glu:
0
0
0
0
15
43
0
15
0
0
43
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
15
0
58
15
0
0
0
0
0
0
0
43
0
% G
% His:
0
15
15
29
0
0
0
0
29
0
15
0
0
0
0
% H
% Ile:
0
0
15
0
0
15
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
29
0
0
43
0
15
0
0
0
% K
% Leu:
0
15
0
0
0
0
0
0
0
0
0
15
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
0
0
0
0
0
15
0
0
15
0
0
15
0
% P
% Gln:
0
0
0
15
0
0
0
15
0
15
15
0
0
15
29
% Q
% Arg:
15
0
0
43
0
15
43
0
0
15
0
0
0
0
43
% R
% Ser:
15
0
43
0
0
0
15
29
15
0
0
15
58
0
0
% S
% Thr:
0
0
15
0
0
15
15
0
15
0
0
0
0
0
15
% T
% Val:
15
0
0
0
15
0
0
0
43
0
0
0
15
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
15
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _